In the frame of a recently initiated partnership, IMol Polish Academy of Sciences and IOCB Prague – Institute of Organic Chemistry and Biochemistry will establish a double-affiliated laboratory. The research group led by Dr. Mattia Morandi will use cryo-EM tomography to understand the enthralling dynamics of vesicles and membranes. It’s great to have you on […]

Prof. Agnieszka Chacińska met Prof. Jan Konvalinka to sign a cooperation agreement between the IMol and IOCB Prague.

Recently, we had a unique opportunity to strengthen the bonds for discoveries and innovations between IMol and Bina – Bridge Innovate Nurture Advance, the translational research unit of the Weizmann Institute of Science. This inspiring meeting, full of great discussions and bold ideas, stamped a milestone in our international collaboration toward future advances. Many thanks […]

At IMol, we like to share our passion for science with society. Follow the link below to hear how Dr. Maciej Ciesla, IMol group leader, guides us through the fascinating world of stem cells. https://www.youtube.com/watch?v=7AdpLtQR68c&t=888s

Z głębokim żalem przyjęliśmy wiadomość o odejściu dr inż. Rafała Wierzchosławskiego Kanclerza Polskiej Akademii Nauk.

The Nobel Prize in Physiology or Medicine 2024 was commented by Prof. Agnieszka Chacińska in TVP Nauka.

We invite you to join our next edition of IMol Science Club with Prof. Dr. Reinhard Lührmann from Max Planck Institute for Multidisciplinary Sciences  During IMol Science Club Prof. Reinhard Lührmann will give a lecture on Structural insights into the cascade of snRNP remodeling steps leading to the formation of activated spliceosome Date: October 23th at 2 p.m. Venue: M. Flisa 6, Warsaw, Poland Host: Prof. Magda […]

Where do we get the energy to live? See engaging interview with Prof. Agnieszka Chacińska: https://www.youtube.com/watch?v=Xk_x4gFmLKw Discussion was introductory part of Copernicus Festival: https://copernicusfestival.com/?fyear=2024

Fascinating interview on search for drugs for incurable diseases! See the Wprost podcast with Prof. Agnieszka Chacińska: https://youtube.com/watch?v=FOxkPFEo2Wc…

How mitochondrial stress affects protein synthesis? In response to cellular stress, the synthesis of some proteins halts while others increase. Dr Tomasz Stępkowski and colleagues led by Prof. Agnieszka Chacińska together with the researchers from the IMol Proteomics core facility led by Dr. Remigiusz Serwa, employed cutting-edge high-throughput omics methods to analyze thousands of nascent […]

Join our next edition of IMol Science Club with Prof. Michal Minczuk that will take place on October 16, 2024 at 2 pm! Prof. Michal Minczuk earned a Master’s degree in Biotechnology (1999) and a PhD in Biological Sciences (2003) from the University of Warsaw. He was an FEBS Postdoctoral Fellow at the MRC, Laboratory of Molecular Biology, Cambridge […]

of the International Institute of Molecular Mechanisms and Machinesof the Polish Academy of Sciences in Warsawfor a 4-year term beginning on December 14, 2024 In accordance with § 4 point 3 and § 6 of the Regulation of the Minister of Science andHigher Education of November 22, 2010 on the competition for the position of […]

The International Scientific Board of IMol will recommend candidates for Research Group Leaders at the meeting held on October 17, 2024. We kindly invite you to join online the International IMol Mini Symposium where you will have a chance to watch the presentations of the candidates. More information: https://imol.institute/seminars/international_imol_mini-symposium/

Why does autism spectrum disorder lead to heightened sensitivity to light? Dr. Justyna Zmorzynska and her team identified that a specific brain region makes animals with autism more sensitive to light. They also discovered the molecular mechanisms of this overreaction and potential treatments to reduce it. Read the publication here: https://www.cell.com/iscience/fulltext/S2589-0042(24)01374-9

IMol’s stand at the Science Picnic was full of future scientists! Congratulations to all of the children who conducted their first biological experiments with us! We hope to work with you in our labs one day! Many thanks to all the organizers.

How proteins are imported into human mitochondria? Many mitochondrial proteins utilize the TIM23 complex for their translocation. Prof. Agnieszka Chacińska and her team showed high conservation of the human TIM23 translocase when compared to highly studied yeast. Klaudia Maruszczak and Piotr Draczkowski used computational tools to get first architectural insights into protein transport into mitochondria […]

Work with us at IMol – we have a few openings! Join us to work in the topics of: -> immunological epigenetics (Paweł Mikulski) – postdoc position -> mitochondria and viruses (Michał Wasilewski/Agnieszka Chacińska) – postdoc position as a postdoctoral researcher or -> RNA biology (Magda Konarska) – PhD student Go to https://www.imol.institute/career-lab to find out […]

We are looking for experienced researchers to develop their own independent groups at our modern and science-friendly facility. We offer furnished laboratory space with access to state-of-the-art technology, excellent core facility and supportive administration. The deadline for applying is August 5th. Read more at https://www.imol.institute/group-leader-positions.

Latest commentary on splicing vulnerability in spliceosome-mutated blood malignancies published in Trends in Biochemical Sciences. IMol Group leader Dr. Maciej Cieśla and Dr. Cristian Bellodi from Lund University Stem Cell Center discuss new findings from the Abdel-Wahab and Bradley labs published in Molecular Cell. Link to the commentary: https://authors.elsevier.com/…/S0968-0004(24)00111-7 Link to the original paper: https://www.sciencedirect.com/…/pii/S1097276524002843…

oin our next edition of IMol Science Club with Prof. Lynne Maquat. Lynne is a Director of the Center of RNA Biology. MaquatLab studiesRNA decay pathways. In her lecture Lynne will talk about nonsense-mediated mRNA decay in human health and disease. Date: June 12th at 2 pm Venue: M. Flisa 6, Warsaw, Poland Host: Piotr […]

We are glad to announce that Dr. Monika Kluzek, who will soon join IMol as a Group Leader, has been awarded the NCN OPUS 26 Grant. The funding will allow her to realize the project which studies intratumoral bacteria that work with cancer cells, reducing the effectiveness of chemotherapy. As Monika says: “We plan to […]

On May 26, Prof. Agnieszka Chacińska was honored to deliver an opening keynote lecture at EMBO – excellence in life sciences FEBS conference in Greece.

We promote science! On June 15, the 27th Science Picnic of the Polish Radio and the Copernicus Science Center will be held at the National Stadium in Warsaw. We invite everyone, especially children, to our stand (family zone, sector F, stand F24). Children visiting us will have the opportunity to: All participants will receive IMol […]

This year once again, Dr. Vanessa Linke from IMol and Dr. Aleksander Jankowski from University of Warsaw conducted the Carpentries workshop on data analytics and visualization in R for scientists. The workshop teaches basic computational skills and working with data. The event gathered 30 participants. Congratulations to the instructors for a great job!

Latest publication in Journal of Cell Biology, with the contribution from IMol scientists: Mayra Borrero, Ben Hur Mussulini, Vanessa Linke, Remigiusz Serwa and Agnieszka Chacinska. The research shows how mitochondrial protease, long time neglected, takes a central role in clearing up the protein import mess. Special congratulations go to Magda Krakowczyk and Piotr Bragoszewski lab […]

Three scientists from IMol are invited to speak at international conferences: -> Agnieszka Chacińska will give a talk at the 128th International Titisee Conference “Organelle Communication: From Fundamental Understanding to Therapeutics” (10-14 April 2024 in Titisee, Germany). For more details, visit: https://www.bifonds.de/titisee…/for-participants.html -> Carlo Vascotto will present at the 8th edition of SupraBio 2024, the […]

Read more (Polish only): https://lnkd.in/dbq_-_Ph https://lnkd.in/dyxjW29e

It introduces new, more stable type of “cap” for mRNA, with the analyses of proteins interacting with the new mRNA cap performed by Dr. Remigiusz Serwa from IMol. -> https://lnkd.in/dZ_mjH5P

Prof. David Tollervey is a head of the group at the The University of Edinburgh He studies regulation of RNA-protein complexes, pioneering molecular and technological aspects in this field of research. Date: April 8th at 2pm. Title of the talk: Lighting Up RNA-protein Interactions Hosts: Magda Konarska & Maciej Cieśla Venue: M. Flisa 6, Warsaw, […]

Prof. Agnieszka Chacińska was appointed a member of the newly created Advisory Team to the President of the Polish Academy of Sciences. The Team aims to develop changes to the rules for evaluating scientific activities quality of the institutions.

The association brings together companies and institutions that aim to actively contribute to the development of biotech ecosystem in Poland. The membership facilitates contact between IMol scientists and companies in order to find project opportunities and collaborators.

Sounds intriguing? Have a look at the latest issue of Frontiers in Molecular Neuroscience and read the latest review by Dr. Justyna Zmorzynska, new IMol Group Leader, and her group. As Justyna says: “In this review, we present state-of-the-art methods to study the brain function in zebrafish. We highlight the potential of zebrafish for neuroscience […]

Interesting research opportunities in Agnieszka Chacińska group. Apply at https://www.imol.institute/career-lab 

Join us for the next IMol Science Club with Dr. Paweł Mikulski, a Group Leader of the Laboratory of Immunological Epigenetics at IMol. 📌The seminar is open to the public. More information and registration 👉 https://www.imol.institute/imol-science-club

Zaktualizowano: 15 mar Prof. Agnieszka Chacińska is invited to deliver keynote lecture at EMBO I FEBS Advanced Lecture Course: Membranes, Lipids and Proteins in Organelle Biogenesis. Agnieszka will open the event with a lecture: Organelle stress responses.

OxiAge – a new database for reversible protein thiol oxidation in aged cells.  Read the publication in Life Science Alliance: https://doi.org/10.26508/lsa.202302300

Today, IMol joins the global community in recognizing Rare Disease Day. We appreciate the importance of awareness about the challenges faced by individuals with rare diseases. Our research aims to develop treatments for mitochondrial diseases.

We are happy to announce that Dr. Justyna Zmorzynska, IMol Group Leader, has been awarded the NCN SONATA BIS grant! Justyna will study how factors related to maternal infection during pregnancy influence the developing brain. She is particularly interested in how these environmental factors change the neuronal connections and brain function in autism spectrum disorder. […]

Join our next edition of IMol Science Club with Prof. Salvador Aznar Benitah from the Institute for Research in Biomedicine (IRB Barcelona). Salvador holds a BSc/MSc in Biochemistry from the McGill University (Montreal, Canada) and PhD in Molecular Biology from the Biomedical Research Institute (Madrid, Spain). During his postdoctoral fellowship at the London Research Institute […]

We have a few openings for postdoc positions. Join us to work in the topics of: Go to https://www.imol.institute/career-lab to find out who we are looking for and spread the news.

Congratulations to Dr. Anna Marusiak on receiving her habilitation degree! The Scientific Council at IBB PAS formally confirmed Anna’s academic degree as a “habilitated doctor” on 30th January 2024, granted with distinction. Anna’s scientific work contributed to the discovery of the oncogenic functions of MLK kinases and their role in driving resistance to cancer treatments.

Prof. Avi Schoeder will be the next speaker at the IMol Science Club. Our guest is a Professor of Chemical Engineering at the Technion – Israel Institute of Technology. He heads the Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies.   Avi will describe the fundamentals of nanotechnology design. Special attention will be dedicated to […]

We are happy to invite you to the next IMol Science Club seminar, the first one in 2024 Our speaker this time is Dr. Justyna Zmorzynska, Group Leader of the Laboratory of Developmental Neurobiology at IMol. In her talk she will unveil the link between mTORC1 hyperactivity and neuropsychiatric disorders. Justyna’s research focuses on neuropsychiatric […]

On January 31, 2024 we hosted at IMol Prof. Krzysztof Jóźwiak, Director of the National Science Centre in Poland. Our guest visited the labs and met with Prof. Agnieszka Chacinska, Director of IMol, and our Group Leaders.

Why we need oxygen and how our brain respires – find out in the interview with Prof. Agnieszka Chacinska on TVN24.pl. The interview for WOŚP was conducted by Tomasz-Marcin Wrona. Click the link to read the full text: https://tvn24.pl/premium/po-co-nam-tlen-oddychanie-zachodzi-nie-tylko-w-plucach-oddycha-rowniez-mozg-7742214

We proudly announce the collaboration between IMol and Bina – Bridge Innovate Nurture Advance, the translational research and innovation unit of the Weizmann Institute of Science. The agreement was signed last Monday, January 22, 2024, by Prof. Irit Sagi, Vice President for Innovation and Technology Transfer at the Weizmann Institute of Science, and Prof. Agnieszka Chacinska, […]

“Drivers of cancer metastasis – Arise early and remain present”, the newest publication by Dr. Dagmara Dymerska and Dr. Anna Marusiak from the Laboratory of Molecular OncoSignalling, was published in the prestigious journal “BBA Reviews on Cancer”! The review explores recent discoveries in genetic factors that drive cancer advancement and metastasis. Have a look at […]

Join our next IMol Science Club! Our guest is Prof. Irit Sagi – Vice President for Innovation and Technology Transfer at the Weizmann Institute of Science, and a member of the Department of Immunology and Regenerative Biology. In her research, she develops and applies unique biophysical approaches to investigate the molecular processes of tissue and […]

Happy Holidays and a Happy New Year from IMol!

Imagine a world where a tiny worm holds the secret to a longer, healthier life! Scientists led by Dr. Pokrzywa (https://pokrzywalab.com/) from the International Institute of Molecular and Cell Biology in Warsaw uncovered a fascinating discovery about S-adenosylhomocysteine (SAH), a special metabolite that seems to unlock the secret to extending the lifespan of these little creatures. […]

Great news! Dr Anna Marusiak (Laboratory of Molecular OncoSignalling) has been awarded the NCN OPUS 25 grant. The funding will allow her to realize the project “Investigating the mechanisms of epithelial/mesenchymal plasticity and metastasis”. As Ania says: “The mechanisms of metastasis formation are not yet fully understood. Our research team will investigate the role of […]

Molecular mechanisms of ageing: how to address the causes, not just symptoms, of age-associated diseases? Check out Dr. Hania Salmonowicz new publication from her PhD studies in Passos_lab, Mayo Clinic published in Nature! It reveals the origins of inflammation in senescent cells: the BAX protein – regulated mitochondrial perforation and the release of mitochondrial content […]

Join us for the next IMol Science Club with Dr. Aleksandra Pękowska to listen to her talk entitled “Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to brain evolution”. Our guest is the head of the Dioscuri Center for Chromatin Biology and Epigenomics at the Nencki Institute of Experimental Biology of the […]

Zaktualizowano: 17 paź 2023 “Polityka” Weekly Magazine announced the finalists of the 23rd edition of POLITYKA Science Awards – a scholarship started in 2001 to promote ” (…) valuable career patterns and scientific achievements of young people of science in Poland “. The search is for those who have passed an important milestone in their professional […]

“Curiosity and the desire to solve puzzles were the main driving force behind my scientific career” – says Prof. Agnieszka Chacińska. On the pages of Gazeta Wyborcza, Agnieszka takes a closer look at her research and the importance of basic science. Read more here .

Join the International IMol Mini-Symposium and meet exceptional scientists selected from large group of international candidates. The event is part of the IMol Scientific Board meeting chaired by Prof. Philip A. Sharp, Nobel Prize laureate. Looking forward to seeing you there! Mor information and registration under the link: https://www.imol.institute/mini-symposium-12-09-2023

Join the forthcoming IMol Science Club Seminar to discover secrets of L-asparaginase with Prof. Alex Wlodawer from National Institutes of Health (NIH) Center for Cancer Research. As a structural biologist he investigates the relationship between protein structure and function, mainly by high-resolution X-ray diffraction. Some of his areas of interest include elucidating structural features of […]

We encourage you to join us for the first IMol Science Club seminar after the summer break. On Friday, August 25, we will host Peter Sicinski from the Department of Genetics, Harvard Medical School, who will give a lecture entitled “Targeting cyclin-dependent kinase 2 (CDK2) for cancer treatment” Our guest is a professor of genetics […]

The recent publication of IMol researchers identifies a novel defense mechanism to restore cellular protein homeostasis upon mitochondrial disease stress. The Chacinska group, with a leading researcher Minji Kim supported by Remigiusz Serwa, a head of the IMol Proteomics Core Facility, discovered a novel stress mechanism activated by defective mitochondria, the powerhouses of the cell. […]

Do you want to find out more about molecular mechanisms of alternative splicing regulation in cancer? Come to the next IMol Science Club Seminar on June 22nd, where we will be joined by Juan Valcárcel of the Centre for Genomic Regulation (CRG) in Barcelona. Prof. Valcárcel is the Deputy Director of the CRG, specializing in […]

For the third time, the prestigious EMBO Long Term Fellowship goes to IMol! Klaudia Maruszczak, a postdoc from the Chacińska lab, has just been awarded the stipend. Mitochondrial dysfunction and resulting impairment of organellar biogenesis leads to a build-up of proteinaceous deposits in the cytosol of the cell. Klaudia will study the mechanism of formation, […]

Another great news! Dr. Agata Kodroń and Dr. Minji Kim from the Chacinska Group and Dr. Paweł Mikulski, who will soon join us as a Group Leader, have been awarded SONATA 18 grants by NCN. Congratulations to all of the three laureates! Read more about the projects here: https://www.ncn.gov.pl/konkursy/wyniki/2023-05-18-opus24-sonata18

Exciting news! Dr. Hanna Salmonowicz from the Szczepanowska group and Dawid Mehlich from the Marusiak group are among the laureates of the START 2023 program from the Foundation for Polish Science. START is the oldest scholarship program in Poland, supporting outstanding young scientists from all fields of science, with the aim of encouraging their further […]

We are excited to share the great news! Agnieszka Chacinska has been elected to be a member of the German National Academy of Sciences Leopoldina, a classical scholarly society that originated in 1652. This distinction has been given to only four Polish scientists before, and Agnieszka is the first elected Polish female member. The objectives […]

It’s been 70 years since the structure of DNA was described for the first time in Nature journal. The mapping of the double helix paved the way for molecular biology. At IMol, we aim to understand the molecular basis of diseases and reveal what stands behind molecular instability. Read the seminal article here: https://www.mskcc.org/teaser/1953-nature-papers-watson-crick-wilkins-franklin.pdf

The registration for Prof. Peter Walter’s lecture is now open. Sign up today – the number of participants is limited! Click here to register: https://www.imol.institute/prof-peter-walter-13-09-2022 Altos Labs – www.altoslabs.com ReMedy – https://www.imol.institute/remedy-project PAN – www.pan.pl FNP – www.fnp.org.pl NCN – www.ncn.gov.pl

Check the update on Prof. Peter Walter’s visit in Poland! Our guest is going to give a lecture on Tuesday, September 13, 2022 at 3:00 pm. It will take place at Ochota Campus in Warsaw and will be preceded by a discussion panel. Mark your calendars – the registration will open soon. Altos Labs – […]

Prof. Peter Walter, head of Altos Labs (San Francisco Bay Area, USA) and a world-renowned molecular biologist, is coming to Poland at the invitation of IMol. Save the date and attend his lecture at IMol Science Club on May 8th 2023, at 3 PM. Read more about our guest here: https://altoslabs.com/team/leadership/peter-walter/ Stay tuned for more […]

The registration for Prof. Peter Walter’s lecture is now open. Sign up today – the number of participants is limited! Click here to register: https://www.imol.institute/prof-peter-walter-08-05-2023 Altos Labs – www.altoslabs.com ReMedy – https://www.imol.institute/remedy-project PAN – www.pan.pl FNP – www.fnp.org.pl NCN – www.ncn.gov.pl

Last but not least, the SONATA BIS 12 grant will also help us understand bunyaviruses through the project “Bunyaviral strategies to reorganize and exploit cellular translation” of Dr. Piotr Gerlach (Laboratory of Structural Virology). As Piotr points out: – With the grant, my lab will study how bunyaviruses reorganize and exploit cellular translation. We will […]

How to eliminate cancer stem cells through targeting RNA modifications and hypoxia signalling pathways? Find out at the next IMol Science Club seminar on April 5th where we will be joined by Kamil Kranc from Barts Cancer Institute of Queen Mary University of London! Kamil is the Deputy Lead of the Centre for Haemato-Oncology at […]

Nicola De Franceschi (Laboratory of Membrane Machines) is another IMol Group Leader awarded the SONATA BIS 12 for his project “Reconstitution of viral double-membrane vesicles: towards in vitro organellogenesis”. As Nicola explains: – The project regards the reconstitution of viral double-membrane vesicles. It aims at studying the mechanisms of membrane rearrangements induced in cells upon […]

Our next project awarded the SONATA BIS 12 grant is “Coordination of the spliceosome expression-to-function during embryonic development” by Dr. Maciej Cieśla (Laboratory of Stem Cell RNA Metabolism). As Maciej describes it: – During development, embryonic stem cells, capable of formation of entire organism are formed. With this project, we will understand how differentiation of […]

Zaktualizowano: 21 mar 2023 We’ve already informed that four of our Group Leaders have been awarded the SONATA BIS 12 grant. In the next few posts, we will take a closer look at their winning projects. Dr. Abdelhalim Azzi (Laboratory of Lipids and Chronobiology) about his his project “Circadian signaling functions of the phosphoinositide phosphatase SHIP2”: […]

Dr. Paweł Mikulski, who will join IMol as a Group Leader in mid-2023, is among the laureates of the NAWA Polish Returns programme. Under this programme Paweł will receive funding for the realization of his project ‘The role of genome architecture and related chromatin modifications in innate immune transcriptional memory of antigen presentation genes’. Congratulations!

We are glad to invite you to the next edition of IMol Science Club on March 22nd. This time we will be joined by Marina Rodnina of Max Planck Institute for Multidisciplinary Sciences. In her talk Prof. Rodnina will summarize the recent advances in understanding the mechanisms of three types of recoding events: stop-codon readthrough, […]

Today we are celebrating Rare Disease Day. There are over 7,000 rare diseases which impact over 300 million people all around the world. Among these conditions are mitochondrial diseases – early degenerations which occur inside the cell. To overcome them is a challenge for scientists and doctors alike. At IMol, we aim to combat the […]

We are glad to announce that the Scientific Board of IMol will be holding their first in-person meeting at our new headquarters on February 28th – March 1st. It is exciting for us to finally be able to gather in person, and in our new facility. The Scientific Board of IMol consists of scientists from […]

We are excited to announce that all four of our Group Leaders who applied for the SONATA BIS 12 grant – Dr. Azzi Abdelhalim, Dr. Maciej Cieśla, Dr. Nicola De Franceschi and Dr. Piotr Gerlach – were granted the funding by the NCN. Congratulations!

Zaktualizowano: 27 sty 2023 It is our pleasure to invite you to the next IMol Science Club seminar, this time with our Group Leader, Nicola de Franceschi! In his lecture Nicola will walk us through the fascinating properties of biological membranes, show us how the cell deforms and splits membranes, and how this can be reconstituted […]

Join us at the next edition of IMol Science Club on January 18th where we will be hosting Jan Konvalinka from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences! Prof. Konvalinka is involved in research in Medicinal Chemistry and Biochemistry, involving antiviral research (HIV and influenza viruses), substrate specificity and […]

We wish you a Christmas full of joy and a happy New Year – the first one from our new home at Flisa 6, Warsaw. May the upcoming year 2023 be a time of happiness, joy and success for us all. Merry Christmas and Happy New Year!

Our colleague and Group Leader, Nicola De Franceschi, has been awarded the Polonez Bis 2 grant by NCN! The project concerns the transport of RNA across mitochondrial membranes. As Nicola describes it: “We aim to understand how coronaviruses export their genomic RNA via a mysterious double-membrane pore, using an in vitro reconstitution approach”. Congratulations Nicola!

Let us meet during the next IMol Science Club seminar on December 16th where we will be joined by Rene Bernards from the Netherlands Cancer Institute, Amsterdam! The head of the Laboratory of Functional Cancer Genetics will talk about unconventional approaches to the treatment of cancer. Prof. Bernards uses genome-wide functional genetics to identify new […]

Let us meet during the next IMol Science Club seminar in which we will be joined by Marcin Nowotny, the head of the Laboratory of Protein Structure at the International Institute of Molecular and Cell Biology in Warsaw. Prof. Nowotny uses structural biology to study enzymes handling nucleic acids. In his lecture, he will present […]

Zaktualizowano: 22 lis 2022 We are proud to announce that IMol labs & offices are now combined and based at Flanders Business Park, Flisa street no 6, Warsaw. The spacious facility has: The complex now houses 7 research groups. The labs are fully functional and research is already underway as our scientists are taking advantage of […]

We are happy to announce that IMol is among the laureates of this year’s edition of Symbol awards, granted to the most important scientific units, representatives of strategic industries and leaders of innovation. Award winners of this nationwide media program excel in their industry, significantly contribute to the development of Poland and therefore become a […]

Zaktualizowano: 30 gru 2022 A new paper dealing with the localization of mRNA on the surface of mitochondria in a model organism of zebrafish has just been published in Life Science Alliance. Agnieszka is the publication’s corresponding author. As Agnieszka says, “The cell is a complicated structure. Many processes are organized spatially, mainly in the eukaryotic […]

Take the opportunity to assume the position of Group Leader in our Institute! We are looking for experienced scientists who will set up independent research groups. Their task will be to develop ambitious and innovative research programmes at the molecular and biochemical level, which will complement the existing research projects at IMol. Please, find out […]

Join us for the next edition of IMol Science Club with Prof. Douglas C. Wallace. This event is a follow-up of the Mitochondrial Disease Awareness Week internationally celebrated on 18-24.09.2022. Our guest, Prof. Douglas C. Wallace, is a geneticist at the University of Pennsylvania and the Children’s Hospital of Philadelphia in Pennsylvania. He pioneered the […]

Join us to listen to prof. Peter Walter’s lecture in Warsaw! The event is open to anyone upon registration: https://www.imol.institute/prof-peter-walter-13-09-2022 Feel free to share! Altos Labs – www.altoslabs.com ReMedy – https://www.imol.institute/remedy-project PAN – www.pan.pl FNP – www.fnp.org.pl NCN – www.ncn.gov.pl

Our colleague, Dr. Hania Salmonowicz from Karolina Szczepanowska group, was awarded a SONATINA NCN grant. Hania’s study at IMol will investigate how aging cells manage to maintain and repair the key energy producing machineries in their mitochondria. Congratulations Hania! NCN – www.ncn.gov.pl EMBO – www.embo.org PAN – www.pan.pl FNP – www.fnp.org.pl

We are proud of Piotr Gerlach whose postdoc project from Elena Conti lab at Max-Planck-Institut für Biochemie in Munich, done in collaboration with Torben Heick Jensen lab at Aarhus University in Denmark, has been published in Molecular Cell. As Piotr explains: ‘RNA exosome is one of the major machineries of our cells that keep our […]

Prof. Peter Walter – the world-renowned molecular biologist, an expert in the field of cellular stress response research and head of Altos Labs (San Francisco Bay Area, USA), is coming to Poland at the invitation of IMol director, Prof. Agnieszka Chacinska. Save the date of 13th September 2022 to meet him in person at the […]

Our colleague, Dr. Hanna Salmonowicz awarded EMBO fellowship. Hania’s study at IMol will help to investigate the OXPHOS system and how this critical molecular machinery responsible for energy production is kept in shape in aged cells. Congratulations Hania! Fundacja na rzecz Nauki Polskiej Polska Akademia Nauk EMBO – excellence in life sciences

If you haven’t come across an interview with Prof. Agnieszka Chacińska in Forum Akademickie yet – here’s the link to the full text: https://forumakademickie.pl/sprawy-nauki/prof-agnieszka-chacinska-system-nie-jest-gotowy-na-nowe-podmioty/ Enjoy your reading! https://www.imol.institute/agnieszka-chacinska The Foundation for Polish Science – https://www.fnp.org.pl/ Polish Academy of Sciences – https://pan.pl/ National Science Centre – https://www.ncn.gov.pl

We are recruiting Group Leaders! Scientific Board of IMol, chaired by the Nobel Prize laureate Prof. Phillip A. Sharp, will recommend candidates for Group Leaders at IMol. The shortlisted candidates will give online presentations at the Mini-Symposium. Speakers: The event is free and open to the public. Please register for the access link https://www.imol.institute/mini-symposium-14-06-2022 Number […]

Scientific Board of IMol, chaired by the Nobel Prize Laureate Phillip A. Sharp, will meet online on June 14-15, 2022. The Board will recommend candidates for Research Group Leaders to the Director of IMol. Full list of IMol Board members is available here: https://www.imol.institute/about-us

“It’s a very exciting time to be a scientist in Poland,” says Dr. Vanessa Linke, EMBO Postdoctoral Fellow at IMol.Take a break to read the full text here: https://www.embo.org/people/bridge-building

Happy to announce that Dr Maciej Cieśla was awarded the NCN OPUS 22 grant, being No.1 on the ranking list in NZ3 panel. The project aims to understand how activation of blood stem cells is regulated at the level of splicing. It will thus help to understand how stem cells are wired to embrace specific […]

Let us meet during the next Science Club seminar. This time the topic “Protein Import Regulation of Mitochondrial Quality Control” will be discussed. The meeting will be run by Prof. Richard Youle from the National Institute on Neurological Disorders and Stroke, NIH, US. See you on June 8th. The seminar is free and open to […]

We encourage you to look inside the latest issue of NAUKA INNOWACJE BIZNES magazine. Find a minute to read an interview with Prof. Agnieszka Chacińska and learn more about our Institute.

We’re happy to announce that Dr Vanessa Linke has been awarded with the FNP Start 2022 stipend. Congratulations Vanessa!

On May 10, 2022, scientists from the ReMedy programme participated in the Symposium “Bridging the scales of molecular machines – from structure to function“. It was held in Goettingen, Germany, and organized within the framework of Sonderforschungsbereich 1190: Compartmental Gates and Contact Sites in Cells (SFB 1190).

Save the date and join the Science Club seminar on May 18th. This time Prof. Rachel Green from Johns Hopkins University will focus on the issues related to the colliding ribosome as a hub for translational regulation. It is a great opportunity to get to know the latest findings. The seminar is free and open […]

The next seminar at the IMol Science Club will be conducted in person by Prof. Jim Naismith from Rosalind Franklin Institute. He will focus on “Intercepting SARS-CoV-2 with nanobodies”. May 4th, 2022, 2 PM CET CeNT Lecture Hall Warsaw, 2C Banacha Str. Prof. Jim Naismith Intercepting SARS-CoV-2 with nanobodies The seminar is open for public. […]

Congratulations to Prof. Agnieszka Chacińska for being ranked #5 in Poland in the 2022 Edition of Research.com ranking of Top 1000 Scientists in the area of Biology and Biochemistry. The ranking is based on the h-index, number of citations and scientific papers published in the field of Biology and Biochemistry.

IMol team is wishing you a Happy Easter filled with lots of spring joy and hope!

If you are interested in stem cells, join our next Science Club seminar. Dr. Maciej Cieśla – the Leader Group of IMol’s Laboratory of Stem Cell RNA Metabolism will talk about Pseudouridine-driven programmes in stem cells and cancer. He will present his findings and analyses. Join the group of listeners. April 13th, 2022, 2 pm. […]

Big chance for dynamic candidates to take up the position of Group Leader in our Institute! We are looking for experienced scientists to set up independent research groups and to develop ambitious and innovative research programmes at the molecular and biochemical level, complementing the existing research projects at IMol. Please, read more about our offer […]

This is the subject of our next IMol Science Club. Join us and listen to Dr. Richard Randall from the University of St Andrews, UK. He is going to share his interesting theses and findings to date. March 30th, 2022, 2 PM CET Richard Randall Fundamental and applied studies on paramyxovirus persistence and defective interfering […]

This is a unique forum for presenting our research and bringing together established and early career researchers to discuss new developments in science. The meeting will feature a Keynote talk from Prof. Peter Rehling, invited presentations from Drs. Sebastian Glatt, Kinga Kamieniarz-Gdula and Krzysztof Szade, together with talks given by several IMol group leaders. The […]

To apply by our fast-track recruitment route, email us to a dedicated address: forukraine@imol.institute and include the most important information about your education, degree, research interests and experience. Our recruitments open now and coming soon: Please follow our website https://www.imol.institute/career-lab to see current openings if you’re interested in specific projects, but it’s also absolutely fine […]

The next seminar at the IMol Science Club will be devoted to the circadian clock. Please, join us and listen to our colleague who is going to share very interesting results of his research. March 16th, 2022, 2 PM CET Abdelhalim Azzi Uncovering the link between the Hippo pathway and circadian clock The seminar is […]

This is a shoutout to biologists, technicians, biotechnologists, bioinformaticians from Ukraine. We’re opening a fast-track recruitment opportunity for scientists from Ukraine to join our Institute. The recruitment procedure is simplified especially for you. We accept informal inquiries, simplified applications, as well as short messages. Just email us to a dedicated address: forukraine@imol.institute and include the […]

We love news like this one! We are happy to announce that Dr. Piotr Gerlach, will join the IMol team in the following months! His research project “Mechanism of the bunyaviral transcription-translation coupling” has been just awarded with EMBO Installation Grant 2020, which is granted each year, to the talented, early-career scientists who are in […]

Congratulations to Dr. Anna Marusiak and Dr. Karolina Szczepanowska from IMol The International Institute of Molecular Mechanisms and Machines, Polish Academy of Sciences – laureates of SONATA BIS grants! This prestigious award from The National Science Centre is addressed to independent researchers who wish to establish their own groups. Our leaders win funds reaching nearly […]

February 16th, 2022, 2 p.m. CET Caroline Dive Cancer Research UK Manchester Inistitute Liquid Biopsies in Lung Cancer The seminar is open for public. For abstract and registration please visit: https://www.imol.institute/imol-science-club

Dzięki inicjatywie dr Marcina Magnusa możecie połączyć dwa w jednym – pomóc dzieciom i poznać bliżej świat nauki poprzez spotkania i warsztaty z naszymi naukowcami. Zapraszamy do licytacji! https://allegro.pl/oferta/spotkanie-przy-kawie-z-prof-agnieszka-chacinska-11736029284 https://allegro.pl/oferta/sztuka-naukowa-dla-dzieci-z-dr-hanna-salmonowicz-11734459089 https://allegro.pl/oferta/warsztaty-z-biologii-rna-z-dr-marcinem-magnusem-11735947261 https://allegro.pl/oferta/warsztaty-z-biol-mitochondriow-z-dr-agata-kodron-11746045443 https://allegro.pl/oferta/spotkanie-przy-kawie-z-prof-magda-konarska-11748659099 https://allegro.pl/oferta/magia-midichlorianow-warsztaty-dr-szczepanowska-11749871324 IMol for WOŚP! IMol takes part in the charity action of WOŚP (the Great Orchestra of Christmas Charity ) – one […]

December is our favorite month. We celebrate two occasions: the first birthday of IMol and festive times of Christmas and New Year. We would like to share with you this special atmosphere and wish you a peaceful and joyful Christmas. Let the coming year 2022 be for us all a productive continuity in a new […]

Congratulations to Dawid Mehlich, PhD student in the Laboratory of Molecular OncoSygnalling, for receiving the Preludium grant! Dawid will be investigating the MLK4 signalling in DNA damage response and cancer therapy. Good luck with your research!

Mehlich et al. identified the novel functions of protein kinase MLK4 in promoting chemoresistance to triple-negative breast cancer (TNBC), the most aggressive subtype of breast cancer. The group discovered that inhibiting MLK4 sensitizes TNBC cells to DNA damaging agents, such as doxorubicin, a commonly used drug in breast cancer treatment. The team also showed the […]

November 3rd, 2021, 2 p.m. CET Piotr Gerlach International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences Bunyaviral polymerase – replication, transcription and beyond. The seminar is open for public. For abstract and registration please visit: https://www.imol.institute/imol-science-club

The vacations are over so we are coming back to the IMol Science Club seminars. This time our speaker is Aleksandra Trifunovic from Institute of Mitochondrial Diseases and Ageing, University of Cologne, Germany. Please, visit https://bit.ly/2ZIUWbV for details, abstract and registration. The seminar is free. After registration the access link will be sent to your […]

Ever wondered how information on oxidative stress is relied from mitochondria to the cytosol? https://9500d8a3-10d6-46dd-b789-a2cb14c8025e.usrfiles.com/html/2b2e4b_d767b483cae16e027c4ea8ac7906fbf4.html In the recent paper from the Wang group, Li et al describe a novel oxidation – driven mechanism concerning the power houses of the cell, mitochondria, and linking oxidation of the protein shaping mitochondria membranes (dMIC60) with removal of mitochondria […]

The IMol Colloquia are the institute’s internal seminars and excellent opportunities for group leaders, students, and postdocs to present their research to colleagues. The seminars take place every two weeks and include insights into planned research, work-in-progress or ready-to-publish work. The goal of IMol Colloquia is to share our scientific achievements, stimulate the interactions within […]

Zaktualizowano: 2 mar 2022 The surprising discovery of Maria Sladowska et al. was just published in PLOS Biology Proteins are the workhorses in the cell. However, the excess of their dysfunctional forms is dangerous. Thus, protein degradation mechanisms evolved to clear such proteins. One major protein clearance pathway involves a complex machine called the proteasome. The […]

The warmest thanks to all the participants of last IMol Science Club talk by Piotr Szwedziak. Almost all of you have stayed until the very last minute of Q&A session, so we dare to hope that you like it. 😉 This talk was the first one from the cycle of lectures we would like to […]

We are recruiting group leaders for “Regenerative Mechanisms for Health” project. All the candidates will present their lectures to the International Science Committee, chaired by a Nobel Laureate – Prof. Phillip A. Sharp. The event is open to the public but the number of participants is limited. When: May 25th, 2:30 p.m. CET Speakers: Please […]

On May 5th, 2021, join us in online science seminar by Piotr Szwedziak – the very first lecture in IMol. The seminar “Amyloid-β oligomer interactions with lipid membranes by cryo-electron tomography” is directed to the open public of all the people interested in this topic. To participate in the seminar you should register at IMol […]

On the of March, The President of Polish Academy of sciences has approved the new Scientific Board of IMol. The Chairman of the SB is prof. Phillip A. Sharp of MIT, Nobel Laureate.

We are proud to announce that Dr. Piotr Szwedziak is among the laureates of the latest Sonata BIS grant by the National Science Center in Poland. His awarded project is focused on the collagen transport in human cells. New project Dr. Szwedziak is a group leader in ReMedy since 2019. He received a PhD from […]

We love news like this one! We are happy to announce that Dr. Piotr Gerlach, will join the IMol team in the following months! His research project “Mechanism of the bunyaviral transcription-translation coupling” has been just awarded with EMBO Installation Grant 2020, which is granted each year, to the talented, early-career scientists who are in […]