The research reveals how targeting protein phosphatases can enhance efficiency of immunotherapy by affecting the spliceosome. Collaborating with Prof. Rene Bernards’ group at Antoni van Leeuwenhoek, Dr. Vladyslava Liudkovska and Dr. Maciej Cieśla from Mol raise a prospect of combining splicing targeting approaches with inhibition of phosphatases PP2A/PP5 in colon cancer.
Congratulations to Maciej, Vlada and co!
Read more here: https://www.embopress.org/…/10.1038/s44319-024-00128-3